منابع مشابه
Database of Structural Motifs in Proteins
SUMMARY The database of structural motifs in proteins (DSMP) contains data relevant to helices, beta-turns, gamma-turns, beta-hairpins, psi-loops, beta-alpha-beta motifs, beta-sheets, beta-strands and disulphide bridges extracted from all proteins in the Protein Data Bank primarily using the PROMOTIF program and implemented as a web-based network service using the SRS. The data corresponding to...
متن کاملIdentifying Structural Motifs in Proteins
In biological macromolecules, structural patterns (motifs) are often repeated across different molecules. Detection of these common motifs in a new molecule can provide useful clues to the functional properties of such a molecule. We formulate the problem of identifying a given structural motif (pattern) in a target protein (example) and discuss the notion of complete matches vis-a-vis partial ...
متن کاملFinding Compact Structural Motifs in Many Proteins
Multiple structural alignment is a fundamental problem in computational biology. Compared with sequence alignment, structural alignment is more powerful in detecting the evolutionary relationship of proteins. A variety of algorithms have been proposed to attack this problem, however, they are either heuristic without theoretical performance guarantee, or inefficient for employing an exhaustive ...
متن کاملTOPDOM: database of conservatively located domains and motifs in proteins
UNLABELLED The TOPDOM database-originally created as a collection of domains and motifs located consistently on the same side of the membranes in α-helical transmembrane proteins-has been updated and extended by taking into consideration consistently localized domains and motifs in globular proteins, too. By taking advantage of the recently developed CCTOP algorithm to determine the type of a p...
متن کاملMALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, we developed an approach based on three ideas. First, an insertion together with a part of the evolutionary core of one domain family (a hybrid motif) is analogous to a similar motif contained within the core of anothe...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2000
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/16.4.372